Leading-edge integrative Treatment for MTHFR genetic mutation

The MTHFR mutation has multiple presentations, significant variances in the specific symptoms and degree of symptoms experienced by different patients.  Accordingly, treatment has to be customized for each patient as there is no one single treatment protocol for all patients.  Immediately below, we present the conditions and symptoms caused or worsened by the MTHFR mutation.  Below this initial table, we present a high-level overview our approach and treatment protocol. Again, we caution patients from attempting to use this protocol without physician supervision.

The foundation of our approach to treating this mutation is our Comprehensive Initial Assessment.  This assessment, which includes 1 ½ hours with one of our physicians provides the basis for establishing the appropriate treatment protocol, taking into consideration the number and degree of your symptoms as well as other health conditions that you have that may or may not be related.

 

Conditions and symptoms caused or made worse by MTHFR mutation

Autism

Addictions: smoking, drugs, alcohol

Miscarriages

Pulmonary embolisms

Depression in Post-Menopausal Women

Schizophrenia

Fibromyalgia and Chronic Fatigue Syndrome

Chemical Sensitivity

Parkinson’s

Irritable Bowel Syndrome

Pre-eclampsia

Stroke

Colorectal Adenoma

Idiopathic male infertility

Blood clots

Rectal cancer

Deficits in childhood cognitive development

Gastric Cancer

Migraines with aura

Low HDL

High homocysteine

Post-menopausal breast cancer

Atherosclerosis

Oral Clefts

Type 1 Diabetes

Epilepsy

Alzheimer’s

Potential drug toxicities: methotrexate, anti-epileptics

Increased bone fracture risk in post-menopausal women

Multiple Sclerosis

Essential Hypertension

Prostate Cancer

Myocardial Infarction (Heart Attack)

Methotrexate Toxicity

Nitrous Oxide Toxicity

Heart Murmurs

Asthma

Shortness of Breath

Bladder Cancer

 

 

Treatment Protocol

Our treatment protocol uses a functional medicine approach.  This is why it begins with our comprehensive initial assessment.  We seek to find root causes to your health issues since many issues you present with are not likely directly caused by the MTHFR mutation.  By using a functional medicine approach, we understand that imbalances in one part of the body may manifest in other systems.  So we avoid the specialist approach that focuses on the disease from a single system view and view the body as a single system of systems.  Using functional medicine as our guide, our treatment protocol is described below.

 1.      Testing.  Advanced testing is the key to our customized treatment programs.  Following are the tests that we used in treating the MTHFR mutation.

a.       Comprehensive lab panel

b.      MTHFR Genotype test

c.       Food sensitivity test

d.      CIMT (due to increased cardiovascular risk)

2.      Dietary Guidelines.  Following are the general dietary guidelines.  The specific guidelines are customized for each patient based on the results of food sensitivity testing.

a.       Eliminate/reduce dairy

b.      Eliminate/reduce gluten

c.       Drink a green smoothie daily

d.      Limit intake of folic acid

e.      Limit intake of processed foods

f.        Avoid antacids

3.      Lifestyle Guidance.  Depending on age , lab results and degree of symptoms, lifestyle adjustments may be required for symptomatic improvement in some patients.  Below are the areas of focus for lifestyle guidance.

a.       Balance hormones with Biodentical Hormone Replacement Therapy where indicated

b.      Eliminate carpeting from the home

c.       Filter chlorine from all water in the household

d.      Cook with electric stove; avoid using gas stoves

4.      Nutritional Supplementation.  This is a cornerstone for many of our programs but is especially important for patients with the MTHFR mutation.  IV Vitamin Therapy provides immediate relief to many patients and oral supplementation helps to sustain these benefits.  Below are the critical areas of nutritional supplementation for most patients.

a.       Broad spectrum IV Vitamin Therapy possibly including amino acids where indicated

b.      Comprehensive multivitamin (without folic acid)

c.       Metholated folate

d.      Glutathione

e.      Fish oil

f.        Nattokinase

g.       Vitamin C

h.      Vitamin D3

i.         Probiotics

Success Stories

Doctor's Note
This patient presented with hormones that were out of balance and extreme hypothyroidism. I took her off the birth control pills (synthetic hormones) treated her with bioidentical hormone replacement and compounded T3/T4. The patient has responded very well in a short period of time.
Patient Response
Hi Lynese -- Great news - seems a fibroid has disappeared! The ultrasound revealed only one fibroid this time, and it is just a little teensy bit smaller than before. So it hasn't gotten any bigger at all. And the other fibroid didn't show up on the ultrasound. smile

Thank goodness I did not get that hysterectomy, huh? and thank goodness I came to you to start the bio-identical hormone therapy. I believe that the progesterone is working. And I'm so glad I'm not on the birth control pills anymore. BTW, haven't had a period since September, and haven't had any hot flashes either! Life is good. smile

AK - Germantown, MD